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p53 coordinates base excision repair to prevent genomic instability
DNA constantly undergoes chemical modification due to endogenous and exogenous mutagens. The DNA base excision repair (BER) pathway is the frontline mechanism handling the majority of these lesions, and primarily involves a DNA incision and subsequent resealing step. It is imperative that these proc...
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| 發表在: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4838360/ https://ncbi.nlm.nih.gov/pubmed/26773055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw015 |
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