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BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management

DNA base damage and non-coding apurinic/apyrimidinic (AP) sites are ubiquitous types of damage that must be efficiently repaired to prevent mutations. These damages can occur in both the nuclear and mitochondrial genomes. Base excision repair (BER) is the frontline pathway for identifying and excisi...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Limpose, Kristin, Corbett, Anita H., Doetsch, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576989/
https://ncbi.nlm.nih.gov/pubmed/28629773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.007
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