Llwytho...

DNA damage mediates changes in neuronal sensitivity induced by the inflammatory mediators, MCP-1 and LPS, and can be reversed by enhancing the DNA repair function of APE1

Although inflammation-induced peripheral sensitization oftentimes resolves as an injury heals, this sensitization can be pathologically maintained and contribute to chronic inflammatory pain. Numerous inflammatory mediators increase the production of reactive oxygen (ROS) and nitrogen species (RNS)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuroscience
Prif Awduron: Fehrenbacher, Jill C., Guo, Chunlu, Kelley, Mark R., Vasko, Michael R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954980/
https://ncbi.nlm.nih.gov/pubmed/28965839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.09.039
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