The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation

Although exposure to ionizing radiation (IR) can produce significant neurotoxicity, the mechanisms mediating this toxicity remain to be determined. Previous studies using neurons isolated from the central nervous system show that IR produces reactive oxygen species and oxidative DNA damage in those...

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Hauptverfasser: Vasko, Michael R., Guo, Chunlu, Thompson, Eric L., Kelley, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162094/
https://ncbi.nlm.nih.gov/pubmed/21741887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.06.004
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