Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress; Use of APE1 small molecule inhibitors to delineate APE1 functions

Oxidative DNA damage has been implicated in a number of central nervous system pathologies. The base excision repair (BER) pathway is one of the most important cellular protection mechanisms that respond to oxidative DNA damage. Human apurinic (apyrimidinic) endonuclease/redox effector factor (APE1/...

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Main Authors: Jiang, Yanlin, Guo, Chunlu, Fishel, Melissa L., Wang, Zheng-Yu, Vasko, Michael R., Kelley, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765866/
https://ncbi.nlm.nih.gov/pubmed/19726241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.08.003
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