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Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress; Use of APE1 small molecule inhibitors to delineate APE1 functions

Oxidative DNA damage has been implicated in a number of central nervous system pathologies. The base excision repair (BER) pathway is one of the most important cellular protection mechanisms that respond to oxidative DNA damage. Human apurinic (apyrimidinic) endonuclease/redox effector factor (APE1/...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jiang, Yanlin, Guo, Chunlu, Fishel, Melissa L., Wang, Zheng-Yu, Vasko, Michael R., Kelley, Mark R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765866/
https://ncbi.nlm.nih.gov/pubmed/19726241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.08.003
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