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IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission
Host factors restricting the transmission of respiratory viruses are poorly characterized. We analyzed the contribution of type I and type III interferon (IFN) using a mouse model in which the virus is selectively administered to the upper airways, mimicking a natural respiratory virus infection. Mi...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953542/ https://ncbi.nlm.nih.gov/pubmed/29651984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33354 |
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