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Depletion of the Insulator Protein CTCF Results in Herpes Simplex Virus 1 Reactivation In Vivo
Herpes simplex virus 1 (HSV-1) establishes a lifelong latent infection in host peripheral neurons, including the neurons of the trigeminal ganglia (TG). HSV-1 can reactivate from neurons to cause recurrent infection. During latency, the insulator protein CTCF occupies DNA binding sites on the HSV-1...
Guardat en:
| Publicat a: | J Virol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5952164/ https://ncbi.nlm.nih.gov/pubmed/29514910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00173-18 |
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