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CTCF Occupation of the Herpes Simplex Virus 1 Genome Is Disrupted at Early Times Postreactivation in a Transcription-Dependent Manner

In herpes simplex virus 1 (HSV-1), binding clusters enriched in CTCF during latency have been previously identified. We hypothesized that CTCF binding to CTCF clusters in HSV-1 would be disrupted in a reactivation event. To investigate, CTCF occupation of three CTCF binding clusters in HSV-1 was ana...

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Detalhes bibliográficos
Main Authors: Ertel, Monica K., Cammarata, Amy L., Hron, Rebecca J., Neumann, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497617/
https://ncbi.nlm.nih.gov/pubmed/22973047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01655-12
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