Cohesin Subunit Rad21 Binds to the Herpes Simplex Virus 1 Genome near CTCF Insulator Sites during Latency In Vivo

Herpes simplex virus 1 (HSV-1) is a human pathogen that can establish a lifelong infection in the host. During latency, HSV-1 genomes are chromatinized and are abundantly associated with histones in sensory neurons, yet the mechanisms that govern the latent-lytic transition remain unclear. We hypoth...

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Bibliographic Details
Published in:J Virol
Main Authors: Singh, Pankaj, Neumann, Donna M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139716/
https://ncbi.nlm.nih.gov/pubmed/33692212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00364-21
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