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Deciphering p53 Signaling in Tumor Suppression
The p53 transcription factor is mutated in over half of human cancers, and p53-null mice are highly predisposed to cancer, highlighting p53’s essential role in tumor suppression. Studies in mouse models have revealed that p53 cell cycle arrest and apoptosis responses to acute DNA damage signals are...
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| Yayımlandı: | Curr Opin Cell Biol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949255/ https://ncbi.nlm.nih.gov/pubmed/29195118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.11.005 |
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