Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure

RATIONALE: Disrupted proteostasis is one major pathological trait that heart failure (HF) shares with other organ proteinopathies, such as Alzheimer’s and Parkinson’s diseases. Yet, differently from the latter, whether and how cardiac preamyloid oligomers (PAOs) develop in acquired forms of HF is un...

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Bibliografski detalji
Izdano u:Circ Res
Glavni autori: Rainer, Peter P., Dong, Peihong, Sorge, Matteo, Fert-Bober, Justyna, Holewinski, Ronald J., Wang, Yuchuan, Foss, Catherine A., An, Steven S., Baracca, Alessandra, Solaini, Giancarlo, Glabe, Charles G., Pomper, Martin G., Van Eyk, Jennifer E., Tomaselli, Gordon F., Paolocci, Nazareno, Agnetti, Giulio
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948147/
https://ncbi.nlm.nih.gov/pubmed/29483093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312082
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