Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure

RATIONALE: Disrupted proteostasis is one major pathological trait that heart failure (HF) shares with other organ proteinopathies, such as Alzheimer’s and Parkinson’s diseases. Yet, differently from the latter, whether and how cardiac preamyloid oligomers (PAOs) develop in acquired forms of HF is un...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circ Res
Egile Nagusiak: Rainer, Peter P., Dong, Peihong, Sorge, Matteo, Fert-Bober, Justyna, Holewinski, Ronald J., Wang, Yuchuan, Foss, Catherine A., An, Steven S., Baracca, Alessandra, Solaini, Giancarlo, Glabe, Charles G., Pomper, Martin G., Van Eyk, Jennifer E., Tomaselli, Gordon F., Paolocci, Nazareno, Agnetti, Giulio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948147/
https://ncbi.nlm.nih.gov/pubmed/29483093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312082
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