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Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
Microtubules (MTs) are key components of the cytoskeleton and play a central role in cell division and development. MT assembly is known to be associated with a structural change in [Formula: see text]-tubulin dimers from kinked to straight conformations. How GTP binding renders individual dimers po...
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| Gepubliceerd in: | eLife |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
eLife Sciences Publications, Ltd
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5945277/ https://ncbi.nlm.nih.gov/pubmed/29652248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34353 |
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