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Microtubule instability driven by longitudinal and lateral strain propagation
Tubulin dimers associate longitudinally and laterally to form metastable microtubules (MTs). MT disassembly is preceded by subtle structural changes in tubulin fueled by GTP hydrolysis. These changes render the MT lattice unstable, but it is unclear exactly how they affect lattice energetics and str...
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| Veröffentlicht in: | PLoS Comput Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467311/ https://ncbi.nlm.nih.gov/pubmed/32877399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008132 |
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