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Microtubule instability driven by longitudinal and lateral strain propagation
Tubulin dimers associate longitudinally and laterally to form metastable microtubules (MTs). MT disassembly is preceded by subtle structural changes in tubulin fueled by GTP hydrolysis. These changes render the MT lattice unstable, but it is unclear exactly how they affect lattice energetics and str...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467311/ https://ncbi.nlm.nih.gov/pubmed/32877399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008132 |
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