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The nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly
The atomic structures of tubulin in a polymerized, straight protofilament, and in a curved conformation bound to a cellular depolymerizer are clearly distinct. Interestingly, the nucleotide content is identical, and in both cases the conformation of the GTP-containing intra-dimer interface is indist...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1386036/ https://ncbi.nlm.nih.gov/pubmed/15959508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03606 |
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