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Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly

The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet polymer that alternates two types of lateral contacts and that directly converts into microtubules, has been proposed to c...

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Detalhes bibliográficos
Main Authors: Wu, Zhanghan, Wang, Hong-Wei, Mu, Weihua, Ouyang, Zhongcan, Nogales, Eva, Xing, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752796/
https://ncbi.nlm.nih.gov/pubmed/19806219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007291
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