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Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly

The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet polymer that alternates two types of lateral contacts and that directly converts into microtubules, has been proposed to c...

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Détails bibliographiques
Auteurs principaux: Wu, Zhanghan, Wang, Hong-Wei, Mu, Weihua, Ouyang, Zhongcan, Nogales, Eva, Xing, Jianhua
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752796/
https://ncbi.nlm.nih.gov/pubmed/19806219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007291
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