A carregar...
Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities
Many neurodegenerative diseases are characterized by impairment of protein quality control mechanisms in neuronal cells. Ineffective clearance of misfolded proteins by the proteasome, autophagy pathways and exocytosis leads to accumulation of toxic protein oligomers and aggregates in neurons. Toxic...
Na minha lista:
| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943907/ https://ncbi.nlm.nih.gov/pubmed/29620053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2018.11 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|