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Targeting the proteostasis network in Huntington’s disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a polyglutamine expansion mutation in the huntingtin protein. Expansions above 40 polyglutamine repeats are invariably fatal, following a symptomatic period characterised by choreiform movements, behavioural abno...
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| Udgivet i: | Ageing Res Rev |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6320389/ https://ncbi.nlm.nih.gov/pubmed/30502498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2018.11.006 |
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