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New directions in therapeutics for Huntington disease

Huntington disease (HD) is an autosomal dominantly inherited neurodegenerative disease that affects motor, cognitive and psychiatric functions, and ultimately leads to death. The pathology of the disease is based on an expansion of CAG repeats in exon 1 of the huntingtin gene on chromosome 4, which...

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Podrobná bibliografie
Vydáno v:Future Neurol
Hlavní autoři: Potkin, Katya T, Potkin, Steven G
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378950/
https://ncbi.nlm.nih.gov/pubmed/30800004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl-2017-0035
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