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Analysis of neuronal phosphoproteome reveals PINK1 regulation of BAD function and cell death

PINK1 mutations that disrupt its kinase activity cause autosomal recessive early onset Parkinson’s disease (PD). Although research in recent years has elucidated a PINK1-Parkin pathway of mitophagy activation that requires PINK1 kinase activity, mitophagy-independent functions of PINK1 and their pos...

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Bibliografske podrobnosti
izdano v:Cell Death Differ
Main Authors: Wan, Huida, Tang, Bin, Liao, Xun, Zeng, Qiufang, Zhang, Zhuohua, Liao, Lujian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943264/
https://ncbi.nlm.nih.gov/pubmed/29234155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0027-x
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