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Analysis of neuronal phosphoproteome reveals PINK1 regulation of BAD function and cell death

PINK1 mutations that disrupt its kinase activity cause autosomal recessive early onset Parkinson’s disease (PD). Although research in recent years has elucidated a PINK1-Parkin pathway of mitophagy activation that requires PINK1 kinase activity, mitophagy-independent functions of PINK1 and their pos...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wan, Huida, Tang, Bin, Liao, Xun, Zeng, Qiufang, Zhang, Zhuohua, Liao, Lujian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943264/
https://ncbi.nlm.nih.gov/pubmed/29234155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0027-x
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