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Quantitative phosphoproteomic profiling of PINK1-deficient cells identifies phosphorylation changes in nuclear proteins

The Parkinson's disease (PD) associated gene PINK1 encodes a protein kinase that mediates the phosphorylation of multiple proteins involved in mitochondrial homeostasis. The broader downstream signaling events mediated by PINK1 kinase activity have not been well documented. We combine quantitat...

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發表在:Mol Biosyst
Main Authors: Qin, Xiaoyan, Zheng, Chaoya, Yates, John R., Liao, Lujian
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343256/
https://ncbi.nlm.nih.gov/pubmed/24626860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb70565j
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