White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease

INTRODUCTION: White matter hyperintensity (WMH) volume on MRI is increased among presymptomatic individuals with autosomal dominant mutations for Alzheimer’s disease (AD). One potential explanation is that WMH, conventionally considered a marker of cerebrovascular disease, are a reflection of cerebr...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Lee, Seonjoo, Zimmerman, Molly E., Narkhede, Atul, Nasrabady, Sara E., Tosto, Giuseppe, Meier, Irene B., Benzinger, Tammie L. S., Marcus, Daniel S., Fagan, Anne M., Fox, Nick C., Cairns, Nigel J., Holtzman, David M., Buckles, Virginia, Ghetti, Bernardino, McDade, Eric, Martins, Ralph N., Saykin, Andrew J., Masters, Colin L., Ringman, John M., Fӧrster, Stefan, Schofield, Peter R., Sperling, Reisa A., Johnson, Keith A., Chhatwal, Jasmeer P., Salloway, Stephen, Correia, Stephen, Jack, Clifford R., Weiner, Michael, Bateman, Randall J., Morris, John C., Mayeux, Richard, Brickman, Adam M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942789/
https://ncbi.nlm.nih.gov/pubmed/29742105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195838
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