Genome-wide Association Studies in Alzheimer’s Disease: A Review

Por Tosto, Giuseppe, Reitz, Christiane
Publicado em 2013

Genetics of Alzheimer’s Disease: the Importance of Polygenic and Epistatic Components

Por Raghavan, Neha, Tosto, Giuseppe
Publicado no Curr Neurol Neurosci Rep (2017)

Genetic Variants in the Fat and Obesity Associated (FTO) Gene and Risk of Alzheimer's Disease

Por Reitz, Christiane, Tosto, Giuseppe, Mayeux, Richard, Luchsinger, Jose A.
Publicado em 2012

Pattern of extrapyramidal signs in Alzheimer’s disease

Por Tosto, Giuseppe, Monsell, Sarah E., Hawes, Stephen E., Mayeux, Richard
Publicado no J Neurol (2015)

Predicting aggressive decline in Mild Cognitive Impairment: The importance of white matter hyperintensities

Por Tosto, Giuseppe, Zimmerman, Molly E., Carmichael, Owen Thomas, Brickman, Adam M.
Publicado em 2014

Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates

Por Tosto, Giuseppe, Monsell, Sarah E., Hawes, Stephen E., Bruno, Giuseppe, Mayeux, Richard
Publicado no J Alzheimers Dis (2015)

The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment

Por Tosto, Giuseppe, Zimmerman, Molly E., Hamilton, Jamie L., T.Carmichael, Owen, Brickman, Adam M.
Publicado no Alzheimers Dement (2015)

White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment

Por Guzman, Vanessa A., Carmichael, Owen T., Schwarz, Christopher, Tosto, Giuseppe, Zimmerman, Molly E., Brickman, Adam M.
Publicado em 2013

The effect of white matter hyperintensities on cognition is mediated by cortical atrophy

Por Rizvi, Batool, Narkhede, Atul, Last, Briana S., Budge, Mariana, Tosto, Giuseppe, Manly, Jennifer J., Schupf, Nicole, Mayeux, Richard, Brickman, Adam M.
Publicado no Neurobiol Aging (2017)

White matter hyperintensities and cerebral amyloidosis: Necessary and sufficient for clinical expression of Alzheimer’s disease?

Por Provenzano, Frank A., Muraskin, Jordan, Tosto, Giuseppe, Narkhede, Atul, Wasserman, Ben T., Griffith, Erica Y., Guzman, Vanessa A., Meier, Irene B., Zimmerman, Molly E., Brickman, Adam M.
Publicado em 2013

Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease

Por Vardarajan, Badri N., Tosto, Giuseppe, Lefort, Roger, Yu, Lei, Bennett, David A., De Jager, Philip L., Barral, Sandra, Reyes-Dumeyer, Dolly, Nagy, Peter L., Lee, Joseph H., Cheng, Rong, Medrano, Martin, Lantigua, Rafael, Rogaeva, Ekaterina, St George-Hyslop, Peter, Mayeux, Richard
Publicado no Neurol Genet (2017)

Polygenic risk score of sporadic late-onset Alzheimer’s disease reveals a shared architecture with the familial and early-onset forms

Por Cruchaga, Carlos, Del-Aguila, Jorge L., Saef, Benjamin, Black, Kathleen, Fernandez, Maria Victoria, Budde, John, Ibanez, Laura, Kapoor, Manav, Tosto, Giuseppe, Mayeux, Richard P., Holtzman, David M., Fagan, Anne M., Morris, John C., Bateman, Randall J., Goate, Alison M., Harari, Oscar
Publicado no Alzheimers Dement (2017)

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer’s disease

Por Tosto, Giuseppe, Fu, Hongjun, Vardarajan, Badri N, Lee, Joseph H, Cheng, Rong, Reyes-Dumeyer, Dolly, Lantigua, Rafael, Medrano, Martin, Jimenez-Velazquez, Ivonne Z, Elkind, Mitchell S V, Wright, Clinton B, Sacco, Ralph L, Pericak-Vance, Margaret, Farrer, Lindsay, Rogaeva, Ekaterina, St George-Hyslop, Peter, Reitz, Christiane, Mayeux, Richard
Publicado no Ann Clin Transl Neurol (2015)

The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease

Por Tosto, Giuseppe, Bird, Thomas D., Bennett, David A., Boeve, Bradley F., Brickman, Adam M., Cruchaga, Carlos, Faber, Kelley, Foroud, Tatiana M., Farlow, Martin, Goate, Alison M., Graff-Radford, Neill R., Lantigua, Rafael, Manly, Jennifer, Ottman, Ruth, Rosenberg, Roger, Schaid, Daniel J., Schupf, Nicole, Stern, Yaakov, Sweet, Robert A., Mayeux, Richard
Publicado no JAMA Neurol (2016)

Polygenic risk scores in familial Alzheimer disease

Por Tosto, Giuseppe, Bird, Thomas D., Tsuang, Debby, Bennett, David A., Boeve, Bradley F., Cruchaga, Carlos, Faber, Kelley, Foroud, Tatiana M., Farlow, Martin, Goate, Alison M., Bertlesen, Sarah, Graff-Radford, Neill R., Medrano, Martin, Lantigua, Rafael, Manly, Jennifer, Ottman, Ruth, Rosenberg, Roger, Schaid, Daniel J., Schupf, Nicole, Stern, Yaakov, Sweet, Robert A., Mayeux, Richard
Publicado no Neurology (2017)

White matter hyperintensities are a core feature of Alzheimer’s disease: Evidence from the Dominantly Inherited Alzheimer Network

Por Lee, Seonjoo, Viqar, Fawad, Zimmerman, Molly E., Narkhede, Atul, Tosto, Giuseppe, Benzinger, Tammie L.S., Marcus, Daniel S., Fagan, Anne M., Goate, Alison, Fox, Nick C., Cairns, Nigel J., Holtzman, David M., Buckles, Virginia, Ghetti, Bernardino, McDade, Eric, Martins, Ralph N., Saykin, Andrew J., Masters, Colin L., Ringman, John M., Ryan, Natalie S., Förster, Stefan, Laske, Christoph, Schofield, Peter R., Sperling, Reisa A., Salloway, Stephen, Correia, Stephen, Jack, Clifford, Weiner, Michael, Bateman, Randall J., Morris, John C., Mayeux, Richard, Brickman, Adam M.
Publicado no Ann Neurol (2016)