White matter hyperintensities are a core feature of Alzheimer’s disease: Evidence from the Dominantly Inherited Alzheimer Network

OBJECTIVE: White matter hyperintensities(WMH) are areas of increased signal on magnetic resonance imaging(MRI) scans that most commonly reflect small vessel cerebrovascular disease. Increased WMH volume is associated with risk and progression of Alzheimer’s disease(AD). These observations are typica...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Lee, Seonjoo, Viqar, Fawad, Zimmerman, Molly E., Narkhede, Atul, Tosto, Giuseppe, Benzinger, Tammie L.S., Marcus, Daniel S., Fagan, Anne M., Goate, Alison, Fox, Nick C., Cairns, Nigel J., Holtzman, David M., Buckles, Virginia, Ghetti, Bernardino, McDade, Eric, Martins, Ralph N., Saykin, Andrew J., Masters, Colin L., Ringman, John M., Ryan, Natalie S., Förster, Stefan, Laske, Christoph, Schofield, Peter R., Sperling, Reisa A., Salloway, Stephen, Correia, Stephen, Jack, Clifford, Weiner, Michael, Bateman, Randall J., Morris, John C., Mayeux, Richard, Brickman, Adam M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884146/
https://ncbi.nlm.nih.gov/pubmed/27016429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24647
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