Impaired default network functional connectivity in autosomal dominant Alzheimer disease

OBJECTIVE: To investigate default mode network (DMN) functional connectivity MRI (fcMRI) in a large cross-sectional cohort of subjects from families harboring pathogenic presenilin-1 (PSEN1), presenilin-2 (PSEN2), and amyloid precursor protein (APP) mutations participating in the Dominantly Inherite...

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Autori principali: Chhatwal, Jasmeer P., Schultz, Aaron P., Johnson, Keith, Benzinger, Tammie L.S., Jack, Clifford, Ances, Beau M., Sullivan, Caroline A., Salloway, Stephen P., Ringman, John M., Koeppe, Robert A., Marcus, Daniel S., Thompson, Paul, Saykin, Andrew J., Correia, Stephen, Schofield, Peter R., Rowe, Christopher C., Fox, Nick C., Brickman, Adam M., Mayeux, Richard, McDade, Eric, Bateman, Randall, Fagan, Anne M., Goate, Allison M., Xiong, Chengjie, Buckles, Virginia D., Morris, John C., Sperling, Reisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776464/
https://ncbi.nlm.nih.gov/pubmed/23884042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182a1aafe
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