Impaired default network functional connectivity in autosomal dominant Alzheimer disease

OBJECTIVE: To investigate default mode network (DMN) functional connectivity MRI (fcMRI) in a large cross-sectional cohort of subjects from families harboring pathogenic presenilin-1 (PSEN1), presenilin-2 (PSEN2), and amyloid precursor protein (APP) mutations participating in the Dominantly Inherite...

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Main Authors: Chhatwal, Jasmeer P., Schultz, Aaron P., Johnson, Keith, Benzinger, Tammie L.S., Jack, Clifford, Ances, Beau M., Sullivan, Caroline A., Salloway, Stephen P., Ringman, John M., Koeppe, Robert A., Marcus, Daniel S., Thompson, Paul, Saykin, Andrew J., Correia, Stephen, Schofield, Peter R., Rowe, Christopher C., Fox, Nick C., Brickman, Adam M., Mayeux, Richard, McDade, Eric, Bateman, Randall, Fagan, Anne M., Goate, Allison M., Xiong, Chengjie, Buckles, Virginia D., Morris, John C., Sperling, Reisa A.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776464/
https://ncbi.nlm.nih.gov/pubmed/23884042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182a1aafe
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