Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer disease

Clinicopathologic evidence suggests the pathology of Alzheimer disease (AD) begins many years prior to cognitive symptoms. Biomarkers are required to identify affected individuals during this asymptomatic (“pre-clinical”) stage to permit intervention with potential disease-modifying therapies design...

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מידע ביבליוגרפי
Main Authors: Fagan, Anne M., Xiong, Chengjie, Jasielec, Mateusz S., Bateman, Randall J., Goate, Alison M., Benzinger, Tammie L.S., Ghetti, Bernardino, Martins, Ralph N., Masters, Colin L., Mayeux, Richard, Ringman, John M., Rossor, Martin N., Salloway, Stephen, Schofield, Peter R., Sperling, Reisa A., Marcus, Daniel, Cairns, Nigel J., Buckles, Virginia D., Ladenson, Jack H., Morris, John C., Holtzman, David M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038930/
https://ncbi.nlm.nih.gov/pubmed/24598588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007901
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