Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease

OBJECTIVE: To identify rare coding variants segregating with late-onset Alzheimer disease (LOAD) in Caribbean Hispanic families. METHODS: Whole-exome sequencing (WES) was completed in 110 individuals from 31 Caribbean Hispanic families without APOE ε4 homozygous carriers. Rare coding mutations segre...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Neurol Genet
Hoofdauteurs: Vardarajan, Badri N., Tosto, Giuseppe, Lefort, Roger, Yu, Lei, Bennett, David A., De Jager, Philip L., Barral, Sandra, Reyes-Dumeyer, Dolly, Nagy, Peter L., Lee, Joseph H., Cheng, Rong, Medrano, Martin, Lantigua, Rafael, Rogaeva, Ekaterina, St George-Hyslop, Peter, Mayeux, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wolters Kluwer 2017
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570674/
https://ncbi.nlm.nih.gov/pubmed/28852706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000178
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items