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Organocatalytic Stereoselective Synthesis of Fluorinated 3,3′-Linked Bisoxindoles

A highly diastereoselective organocatalytic method that produces 3-fluoro-3′-hydroxy-3,3′-bisoxindoles and the corresponding 3-fluoro-3′-amino derivatives having two adjacent chirality centers from fluorooxindoles and isatins in high yields is described. The reaction occurs in protic solvents at roo...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Moskowitz, Max, Balaraman, Kaluvu, Wolf, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939997/
https://ncbi.nlm.nih.gov/pubmed/29313686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03084
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