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Organocatalytic Stereoselective Synthesis of Fluorinated 3,3′-Linked Bisoxindoles

A highly diastereoselective organocatalytic method that produces 3-fluoro-3′-hydroxy-3,3′-bisoxindoles and the corresponding 3-fluoro-3′-amino derivatives having two adjacent chirality centers from fluorooxindoles and isatins in high yields is described. The reaction occurs in protic solvents at roo...

詳細記述

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書誌詳細
出版年:J Org Chem
主要な著者: Moskowitz, Max, Balaraman, Kaluvu, Wolf, Christian
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939997/
https://ncbi.nlm.nih.gov/pubmed/29313686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03084
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