Llwytho...
Stereoselective Synthesis of 3,3′-Bisindolines by Organocatalytic Michael Additions of Fluorooxindole Enolates to Isatylidene Malononitriles in Aqueous Solution
A highly diastereoselective organocatalytic reaction for the synthesis of fluorinated 3,3′-bisindolines exhibiting adjacent tetrasubstituted carbon stereocenters is described. A broad variety of heterochiral bisindolines was prepared in 91-99% yield using 3-fluorooxindoles and isatylidene malononitr...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Adv Synth Catal |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5939588/ https://ncbi.nlm.nih.gov/pubmed/29755308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201701107 |
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