טוען...
Rational Design of Pyridyl Derivatives of Vanillin for the Treatment of Sickle Cell Disease
Hypoxia-induced polymerization of sickle hemoglobin (Hb S) is the principal phenomenon that underlays the pathophysiology and morbidity associated with sickle cell disease (SCD). Opportunely, as an allosteric protein, hemoglobin (Hb) serves as a convenient and potentially critical druggable target....
שמור ב:
| הוצא לאור ב: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935541/ https://ncbi.nlm.nih.gov/pubmed/29655608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.04.015 |
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