Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease

Candidate drugs to counter intracellular polymerization of deoxygenated sickle hemoglobin (Hb S) continue to represent a promising approach to mitigating the primary cause of the pathophysiology associated with sickle cell disease (SCD). One such compound is the naturally occurring antisickling agen...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Pharm
Päätekijät: Xu, Guoyan G., Pagare, Piyusha P., Ghatge, Mohini S., Safo, Ronni P., Gazi, Aheema, Chen, Qiukan, David, Tanya, Alabbas, Alhumaidi B., Musayev, Faik N., Venitz, Jürgen, Zhang, Yan, Safo, Martin K., Abdulmalik, Osheiza
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871537/
https://ncbi.nlm.nih.gov/pubmed/28858508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00553
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