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Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease

Candidate drugs to counter intracellular polymerization of deoxygenated sickle hemoglobin (Hb S) continue to represent a promising approach to mitigating the primary cause of the pathophysiology associated with sickle cell disease (SCD). One such compound is the naturally occurring antisickling agen...

詳細記述

保存先:
書誌詳細
出版年:Mol Pharm
主要な著者: Xu, Guoyan G., Pagare, Piyusha P., Ghatge, Mohini S., Safo, Ronni P., Gazi, Aheema, Chen, Qiukan, David, Tanya, Alabbas, Alhumaidi B., Musayev, Faik N., Venitz, Jürgen, Zhang, Yan, Safo, Martin K., Abdulmalik, Osheiza
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871537/
https://ncbi.nlm.nih.gov/pubmed/28858508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00553
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