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Quantifying allosteric communication via both concerted structural changes and conformational disorder with CARDS

Allosteric (i.e. long-range) communication within proteins is crucial for many biological processes, such as the activation of signaling cascades in response to specific stimuli. However, the physical basis for this communication remains unclear. Existing computational methods for identifying allost...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Chem Theory Comput
मुख्य लेखकों: Singh, Sukrit, Bowman, Gregory R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934993/
https://ncbi.nlm.nih.gov/pubmed/28282132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01181
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