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Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication

Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are visited by the protein also in the absence of effector ligands. Previously, we deve...

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Detalhes bibliográficos
Main Authors: Mitternacht, Simon, Berezovsky, Igor N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234217/
https://ncbi.nlm.nih.gov/pubmed/22174669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002301
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