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Binding Leverage as a Molecular Basis for Allosteric Regulation
Allosteric regulation involves conformational transitions or fluctuations between a few closely related states, caused by the binding of effector molecules. We introduce a quantity called binding leverage that measures the ability of a binding site to couple to the intrinsic motions of a protein. We...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174156/ https://ncbi.nlm.nih.gov/pubmed/21935347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002148 |
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