טוען...
Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors
Transcription regulation by steroid hormones, vitamin derivatives, and metabolites is mediated by nuclear receptors (NRs), which play an important role in ligand-dependent gene expression and human health. NRs function as homodimers or heterodimers and are involved in a combinatorial, coordinated an...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309777/ https://ncbi.nlm.nih.gov/pubmed/22355136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118192109 |
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