Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR–RXR

Retinoic acid receptors (RARs) as a functional heterodimer with retinoid X receptors (RXRs), bind a diverse series of RA-response elements (RAREs) in regulated genes. Among them, the non-canonical DR0 elements are bound by RXR–RAR with comparable affinities to DR5 elements but DR0 elements do not ac...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Osz, Judit, McEwen, Alastair G, Bourguet, Maxime, Przybilla, Frédéric, Peluso-Iltis, Carole, Poussin-Courmontagne, Pierre, Mély, Yves, Cianférani, Sarah, Jeffries, Cy M, Svergun, Dmitri I, Rochel, Natacha
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515732/
https://ncbi.nlm.nih.gov/pubmed/32974652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa697
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