Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor

Retinoid X receptors (RXRs) act as homodimers or heterodimerisation partners of class II nuclear receptors. RXR homo- and heterodimers bind direct repeats of the half-site (A/G)G(G/T)TCA separated by 1 nucleotide (DR1). We present a structural characterization of RXR-DNA binding domain (DBD) homodim...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Osz, Judit, McEwen, Alastair G., Poussin-Courmontagne, Pierre, Moutier, Emmanuel, Birck, Catherine, Davidson, Irwin, Moras, Dino, Rochel, Natacha
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314640/
https://ncbi.nlm.nih.gov/pubmed/25645674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08216
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