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Quantifying allosteric communication via both concerted structural changes and conformational disorder with CARDS

Allosteric (i.e. long-range) communication within proteins is crucial for many biological processes, such as the activation of signaling cascades in response to specific stimuli. However, the physical basis for this communication remains unclear. Existing computational methods for identifying allost...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Singh, Sukrit, Bowman, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934993/
https://ncbi.nlm.nih.gov/pubmed/28282132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01181
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