Quantifying allosteric communication via both concerted structural changes and conformational disorder with CARDS

Autor Singh, Sukrit, Bowman, Gregory R.
Vydáno v J Chem Theory Comput (2017)

Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding

Autor Sun, Xianqiang, Singh, Sukrit, Blumer, Kendall J, Bowman, Gregory R
Vydáno v eLife (2018)

The small molecule JIB-04 disrupts O(2) binding in the Fe-dependent histone demethylase KDM4A/JMJD2A()

Autor Cascella, Barbara, Lee, Soon Goo, Singh, Sukrit, Jez, Joseph M., Mirica, Liviu M.
Vydáno v Chem Commun (Camb) (2017)

Lithium protects against glucocorticoid induced neural progenitor cell apoptosis in the developing cerebellum

Autor Cabrera, Omar, Dougherty, Joseph, Singh, Sukrit, Swiney, Brant S., Farber, Nuri B., Noguchi, Kevin K.
Vydáno 2013

Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily

Autor Nelson, Christopher A., Epperson, Megan L., Singh, Sukrit, Elliott, Jabari I., Fremont, Daved H.
Vydáno v Viruses (2015)

Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-Lactam

Autor Patrick, Garrett J., Fang, Luting, Schaefer, Jacob, Singh, Sukrit, Bowman, Gregory R., Wencewicz, Timothy A.
Vydáno v Biochemistry (2017)

SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential

Autor Vithani, Neha, Ward, Michael D., Zimmerman, Maxwell I., Novak, Borna, Borowsky, Jonathan H., Singh, Sukrit, Bowman, Gregory R.
Vydáno v bioRxiv (2020)

SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential

Autor Vithani, Neha, Ward, Michael D., Zimmerman, Maxwell I., Novak, Borna, Borowsky, Jonathan H., Singh, Sukrit, Bowman, Gregory R.
Vydáno v Biophys J (2021)

Dexmedetomidine Protects Against Glucocorticoid Induced Progenitor Cell Apoptosis in Neonatal Mouse Cerebellum

Autor O’Connor, Shawn David, Cabrera, Omar Hoseá, Dougherty, Joseph D., Singh, Sukrit, Swiney, Brant Stephen, Salinas-Contreras, Patricia, Farber, Nuri Bradford, Noguchi, Kevin Kiyoshi
Vydáno v J Matern Fetal Neonatal Med (2017)

Defining NADH-driven Allostery Regulating Apoptosis-Inducing Factor

Autor Brosey, Chris A., Ho, Chris, Long, Winnie Z., Singh, Sukrit, Burnett, Kathryn, Hura, Greg L., Nix, Jay C., Bowman, Gregory R., Ellenberger, Tom, Tainer, John A.
Vydáno v Structure (2016)

Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance

Autor Brown, Cameron A., Hu, Liya, Sun, Zhizeng, Patel, Meha P., Singh, Sukrit, Porter, Justin R., Sankaran, Banumathi, Prasad, B. V. Venkataram, Bowman, Gregory R., Palzkill, Timothy
Vydáno v J Biol Chem (2020)

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

Autor Cubuk, Jasmine, Alston, Jhullian J., Incicco, J. Jeremías, Singh, Sukrit, Stuchell-Brereton, Melissa D., Ward, Michael D., Zimmerman, Maxwell I., Vithani, Neha, Griffith, Daniel, Wagoner, Jason A., Bowman, Gregory R., Hall, Kathleen B., Soranno, Andrea, Holehouse, Alex S.
Vydáno v bioRxiv (2020)

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

Autor Cubuk, Jasmine, Alston, Jhullian J., Incicco, J. Jeremías, Singh, Sukrit, Stuchell-Brereton, Melissa D., Ward, Michael D., Zimmerman, Maxwell I., Vithani, Neha, Griffith, Daniel, Wagoner, Jason A., Bowman, Gregory R., Hall, Kathleen B., Soranno, Andrea, Holehouse, Alex S.
Vydáno v Nat Commun (2021)

SARS-CoV-2 Simulations Go Exascale to Capture Spike Opening and Reveal Cryptic Pockets Across the Proteome

Autor Zimmerman, Maxwell I., Porter, Justin R., Ward, Michael D., Singh, Sukrit, Vithani, Neha, Meller, Artur, Mallimadugula, Upasana L., Kuhn, Catherine E., Borowsky, Jonathan H., Wiewiora, Rafal P., Hurley, Matthew F. D., Harbison, Aoife M, Fogarty, Carl A, Coffland, Joseph E., Fadda, Elisa, Voelz, Vincent A., Chodera, John D., Bowman, Gregory R.
Vydáno v bioRxiv (2020)

SARS-CoV-2 Simulations Go Exascale to Capture Spike Opening and Reveal Cryptic Pockets Across the Proteome

Autor Zimmerman, Maxwell I., Porter, Justin R., Ward, Michael D., Singh, Sukrit, Vithani, Neha, Meller, Artur, Mallimadugula, Upasana L., Kuhn, Catherine E., Borowsky, Jonathan H., Wiewiora, Rafal P., Hurley, Matthew F. D., Harbison, Aoife M, Fogarty, Carl A, Coffland, Joseph E., Fadda, Elisa, Voelz, Vincent A., Chodera, John D., Bowman, Gregory R.
Vydáno v Nat Chem (2021)