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SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential

Coronaviruses have caused multiple epidemics in the past two decades, in addition to the current COVID-19 pandemic that is severely damaging global health and the economy. Coronaviruses employ between 20 and 30 proteins to carry out their viral replication cycle, including infection, immune evasion,...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Vithani, Neha, Ward, Michael D., Zimmerman, Maxwell I., Novak, Borna, Borowsky, Jonathan H., Singh, Sukrit, Bowman, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007187/
https://ncbi.nlm.nih.gov/pubmed/33794150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.03.024
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