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Quantifying allosteric communication via both concerted structural changes and conformational disorder with CARDS

Allosteric (i.e. long-range) communication within proteins is crucial for many biological processes, such as the activation of signaling cascades in response to specific stimuli. However, the physical basis for this communication remains unclear. Existing computational methods for identifying allost...

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Dades bibliogràfiques
Publicat a:J Chem Theory Comput
Autors principals: Singh, Sukrit, Bowman, Gregory R.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934993/
https://ncbi.nlm.nih.gov/pubmed/28282132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01181
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