Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease

IMPORTANCE: Older age, high levels of β-amyloid (Aβ), and the presence of the apolipoprotein E (APOE) ε4 allele are risk factors for Alzheimer disease (AD). However, the extent to which increasing age, Aβ, and ε4 are associated with memory decline remains unclear, and the age at which memory decline...

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Pubblicato in:JAMA Neurol
Autori principali: Lim, Yen Ying, Kalinowski, Pawel, Pietrzak, Robert H., Laws, Simon M., Burnham, Samantha C., Ames, David, Villemagne, Victor L., Fowler, Christopher J., Rainey-Smith, Stephanie R., Martins, Ralph N., Rowe, Christopher C., Masters, Colin L., Maruff, Paul T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2018
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933393/
https://ncbi.nlm.nih.gov/pubmed/29356823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.4325
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