KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden

A single nucleotide polymorphism, rs17070145, in the KIdney and BRAin expressed protein (KIBRA) gene has been associated with cognition and hippocampal volume in cognitively normal (CN) individuals. However, the impact of rs17070145 on longitudinal cognitive decline and hippocampal atrophy in CN adu...

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מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Porter, Tenielle, Burnham, Samantha C., Doré, Vincent, Savage, Greg, Bourgeat, Pierrick, Begemann, Kimberly, Milicic, Lidija, Ames, David, Bush, Ashley I., Maruff, Paul, Masters, Colin L., Rowe, Christopher C., Rainey-Smith, Stephanie, Martins, Ralph N., Groth, David, Verdile, Giuseppe, Villemagne, Victor L., Laws, Simon M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794989/
https://ncbi.nlm.nih.gov/pubmed/29391469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20513-y
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