KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden

A single nucleotide polymorphism, rs17070145, in the KIdney and BRAin expressed protein (KIBRA) gene has been associated with cognition and hippocampal volume in cognitively normal (CN) individuals. However, the impact of rs17070145 on longitudinal cognitive decline and hippocampal atrophy in CN adu...

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Publicado no:Sci Rep
Main Authors: Porter, Tenielle, Burnham, Samantha C., Doré, Vincent, Savage, Greg, Bourgeat, Pierrick, Begemann, Kimberly, Milicic, Lidija, Ames, David, Bush, Ashley I., Maruff, Paul, Masters, Colin L., Rowe, Christopher C., Rainey-Smith, Stephanie, Martins, Ralph N., Groth, David, Verdile, Giuseppe, Villemagne, Victor L., Laws, Simon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794989/
https://ncbi.nlm.nih.gov/pubmed/29391469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20513-y
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