SPON1 Is Associated with Amyloid-β and APOE ε4-Related Cognitive Decline in Cognitively Normal Adults

Abstract. BACKGROUND: Genetic variation in Spondin-1, specifically rs11023139, has been associated with reduced rates of cognitive decline in individuals with Alzheimer’s disease. OBJECTIVE: The aim of this study was to assess whether the association was present in cognitively normal older adults. M...

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Veröffentlicht in:J Alzheimers Dis Rep
Hauptverfasser: Fernandez, Shane, Burnham, Samantha C., Milicic, Lidija, Savage, Greg, Maruff, Paul, Peretti, Madeline, Sohrabi, Hamid R., Lim, Yen Ying, Weinborn, Michael, Ames, David, Masters, Colin L., Martins, Ralph N., Rainey-Smith, Stephanie, Rowe, Christopher C., Salvado, Olivier, Groth, David, Verdile, Giuseppe, Villemagne, Victor L., Porter, Tenielle, Laws, Simon M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2021
Schlagworte:
Research Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990462/
https://ncbi.nlm.nih.gov/pubmed/33782664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-200246
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