Amyloid-Related Memory Decline in Preclinical Alzheimer’s Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months

High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cognitively normal (CN) older adults. However, the relationship between these two biomarkers and cognitive decline is unclear. The aim of this study was to investigate the r...

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Опубликовано в: :PLoS One
Главные авторы: Thai, Christine, Lim, Yen Ying, Villemagne, Victor L., Laws, Simon M., Ames, David, Ellis, Kathryn A., Rainey-Smith, Stephanie R., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Maruff, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592244/
https://ncbi.nlm.nih.gov/pubmed/26430784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139082
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