Amyloid-Related Memory Decline in Preclinical Alzheimer’s Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months

High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cognitively normal (CN) older adults. However, the relationship between these two biomarkers and cognitive decline is unclear. The aim of this study was to investigate the r...

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Publicat a:PLoS One
Autors principals: Thai, Christine, Lim, Yen Ying, Villemagne, Victor L., Laws, Simon M., Ames, David, Ellis, Kathryn A., Rainey-Smith, Stephanie R., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Maruff, Paul
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592244/
https://ncbi.nlm.nih.gov/pubmed/26430784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139082
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